PoEdit generates *.mo files from *.po files. This CLI batch (make_mo.bat) file for windows saves time:

set langname=ta_IN
set poedpath=C:\Program Files\Poedit\bin\
copy %langname%.po "%poedpath%"
set abc=%cd%
cd "%poedpath%"
msgfmt %langname%.po -o %langname%.mo

move %langname%.mo "%abc%"
del %langname%.po
cd %abc%
set abc=

Customize the first two lines to suit your language and PoEdit path and place it in the folder having the *.po file and execute it. The *.mo file will get generated in it now.